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One of the fundamental missions of the Department of Orthopaedic Surgery at the University of California, Irvine is the advancement of musculoskeletal medicine and healthcare. It is this critical mission that helps to define our orthopaedic department. Towards this end, we have five full time research laboratories at multiple locations within the University of California, Irvine including the Irvine main campus, UC Irvine Medical Center, and the Long Beach VA Medical Center.

Currently there are eight active grants, totaling $3,043,227 in extramural funding. The department was also among the top 50 US departments of orthopaedic surgery in terms of NIH funding. In 2006 alone, two of our core faculty members won two of the major research awards in musculoskeletal medicine, i.e. the Neer award for the American Shoulder and Elbow Surgeons and the Kappa Delta Young Investigator Award from the Orthopaedic Research Society and American Academy of Orthopaedic Surgery (Dr. Ranjan Gupta).

The following are the current areas of research excellence in the Department of Orthopaedic Surgery.

Neuromuscular Research Laboratory (P.I.: Vince J. Caiozzo, Ph.D.)

Dr. Caiozzo’s laboratory focuses on muscle physiology and mechanics, especially in regard to space exploration and orthopedics.

Peripheral Nerve Research Laboratory ( P.I.: Ranjan Gupta, M.D.)

Dr. Gupta’s laboratory focuses on the Schwann cell control of neural injury with an emphasis on understanding the molecular pathogenesis of chronic nerve injuries, improving treatments for spinal cord injury, and exploring the role of neural injury with rotator cuff injuries.